Antibodies Immunoreactive With Formalin-Fixed Tissue Antigens Recognize Linear Protein Epitopes
نویسندگان
چکیده
منابع مشابه
Antibodies immunoreactive with formalin-fixed tissue antigens recognize linear protein epitopes.
It is not clearly understood why some monoclonal antibodies bind to their antigens informalin-fixed, paraffin-embedded tissue sections but others do not. To address this question, we analyzed the protein epitopes of 9 monoclonal antibodies that are immunoreactive after formalin fixation and antigen retrieval. We identified the antibody contact sites by using phage display and synthesized corres...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2006
ISSN: 0002-9173
DOI: 10.1309/6h0a-rqf7-k3y6-08eh